Everything you need from GRADEing your systematic review, to developing your guideline and beyond


An all-in-one web solution for summarizing and presenting information for health care decision making

GRADEpro supports creating concise summary tables for systematic reviews, facilitates the clinical practice guideline development process and streamlines making recommendations for public health or health policy decisions. GRADEpro is used by over 37 000 reviewers and guideline developers worldwide.

Key features of GRADEpro

Best for both worlds

A tool for guideline developers and authors of systematic reviews.

Works online and offline

You can use GRADEpro both with and without an Internet connection. In order to work offline you will need to set up your account by connecting online at least once.

Simplifies the guideline development process

Follow the whole process of developing recommendations in health care. All in sequence. All in one place.

Produce apps for mobile devices

With GRADEpro you prepare information that may easily be converted into an app for mobile devices.

Easy creation of evidence tables

Create GRADE Evidence Profiles, Cochrane Summary of Findings tables and their variations, adjusted to the type of available information.

Facilitates work with group members

There is a support for various polling and voting activities that working groups perform during the recommendation development process.

Backs up your data on a secure server

You can now share your work and access your documents from any computer in the world.

A tool trusted and used by influential
experts worldwide

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GRADEpro software is used in the guideline development process by
many global medical institutions and associations including WHO, WAO, ATS, ERS, ESICM, SCCM.

Engineered by

Evidence Prime

Supported by


Developed by

GRADE Working Group
GRADEpro results from many years of research, discussion, inspiration, encouragement and criticism of GRADE Working Group members, users of GRADEpro, and many others from multiple countries and insitutions. They all have contributed to the evolution of GRADEpro and many continue advising, testing, and providing feedback. We are grateful to them all.
  • Holger Schünemann

  • Jan Brożek

  • Nancy Santesso

  • Wojtek Wiercioch

  • Tejan Baldeh

  • Yuan (Ray) Zhang

  • Sérgio Kowalski

  • Romina Brignardello-Petersen

  • Alonso Carrasco Labra

  • Matthew Ventresca

  • Itziar Etxeandia Ikobaltzeta

  • Gian Paolo Morgano

  • Carlos A. Cuello Garcia

  • Ignacio Neumann

Technical Advisory Group

  • Alfonso Iorio

  • Reem Mustafa

  • Elie Akl

  • Pablo Alonso

  • Lorenzo Moja

  • Jörg Meerpohl

  • Andy Oxman

  • Yngve Falck-Ytter

  • Shaun Treweek

  • Linn Brandt

  • Susan Norris

  • Laragh Gollogly

  • Faruque Ahmed

  • Ilkka Kunnamo

  • Craig Whittington

  • Judith Thornton

  • Beth Shaw

  • Duncan Service

  • Chris Mavergames

  • Gert van Valkenhoef

  • Rasmus Moustgaard